CItation


AlloSigMA 2: paving the way to designing allosteric effectors and to exploring allosteric effects of mutations Z. W. Tan, E. Guarnera, W.-V. Tee and I. N. Berezovsky. Nucleic Acids Research, 2020, DOI: 10.1093/nar/gkaa338

AlloSigMA: allosteric signaling and mutation analysis server E. Guarnera, W.-V. Tee, Z. W. Tan and I. N. Berezovsky. Bioinformatics, 2017 vol. 33 (24) p. 3996-3998

Additional citations

Structure-Based Statistical Mechanical Model

Structure-Based Statistical Mechanical Model Accounts for the Causality and Energetics of Allosteric Communication. E. Guarnera and I. N. Berezovsky. PLoS Comput Biol, 2016 vol. 12 (3) p. e1004678.

Allosteric mutation

Toward Allosterically Increased Catalytic Activity of Insulin Degrading Enzyme (IDE) Against Amyloid Peptides. I. V. Kurochkin, E. Guarnera, J. H. Wong, F. Eisenhaber, and I. N. Berezovsky. Biochemistry, 2016 vol. 56 (1) p. 228-239.

Reverse perturbation

Reversing allosteric communication: From detecting allosteric sites to inducing and tuning targeted allosteric response. W.-V. Tee, E. Guarnera and I. N. Berezovsky. PLoS Comput Biol, 2018 vol. 14 (6) p. e1006228.

Allosteric polymorphism

On the Allosteric Effect of nsSNPs and the Emerging Importance of Allosteric Polymorphism. W.-V. Tee, E. Guarnera and I. N. Berezovsky. J Mol Biol, 2019 vol. 431 (19) p. 3933-3942.

Toward design of allosteric effectors

Learning About Allosteric Drugs and Ways to Design Them. Z. W. Tan, W.-V. Tee and I. N. Berezovsky. J Mol Biol, 2022 vol. 434 (17) p. 167692.

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Contact information

Former group members
  • Enrico Guarnera
  • Zhen Wah Tan
  • Zejun Zheng